Atherosclerosis
is the root cause of the majority of cardiovascular diseases (CVD). Although
the pathogenesis of the disease is extremely complex, atherosclerosis is characterized by an accumulation of low density lipoproteins in the vascular wall. The development of the disease can lead to a narrowing of the lumen,
known as a stenosis.
Histologically, the American Heart Association classifies
the advancement of a plaque by its composition. Type VI lesions include those
where thrombosis has been generated by exposure of the plaque core. This
clinical event is known as atherosclerotic plaque rupture and can lead to
ischemia. The symptoms and severity of this depend on the location of the
disease. The more severe consequences of atherosclerosis are heart attack and
stroke, caused by ischemia in the coronary and carotid arteries respectively. Read More>>>>>>>>>>>>>>>>
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