Magnetic Resonance Elastography through Atherosclerosis

Atherosclerosis is the root cause of the majority of cardiovascular diseases (CVD). Although the pathogenesis of the disease is extremely complex, atherosclerosis is characterized by an accumulation of low density lipoproteins in the vascular wall. The development of the disease can lead to a narrowing of the lumen, known as a stenosis. 

Atherosclerosis

Histologically, the American Heart Association classifies the advancement of a plaque by its composition. Type VI lesions include those where thrombosis has been generated by exposure of the plaque core. This clinical event is known as atherosclerotic plaque rupture and can lead to ischemia. The symptoms and severity of this depend on the location of the disease. The more severe consequences of atherosclerosis are heart attack and stroke, caused by ischemia in the coronary and carotid arteries respectively. Read More>>>>>>>>>>>>>>>>

Aerobic Training Effect on Blood S-Klotho Levels in Coronary Artery Disease Patients

Aerobic exercise and Klotho gene expression could reduce the risk of cardiovascular events in patients with prior coronaryartery disease (CAD), thus aerobic exercise may decrease the risk of mortality. 

Aerobic exercise can decrease the incidence and severity of cardiac events during exercise among an unselected group of patients with stable CAD. In addition, exercise training improves endotheliumdependent vasodilatation both in epicardial coronary vessels and in resistance vessels in patients with CAD . Patients with significant CAD present lower soluble concentrations of α-Klotho (s-Klotho), as well as reduced levels of Klotho gene expression in the vascular wall. Read more>>>>>>>>>>>>>>

Is it Practical to Search for Masked Hypertension?

Hypertension is an important public health challenge worldwide. It has been identified as the first cause of death worldwide being responsible for 9.4 million premature deaths. Moreover, it has been ranked third as a cause of disability adjusted life-years deteriorating health related quality of life. Hypertension is one of the most frequent reasons for adults to visit a physician´s office, and 33% of US adults ≥ 20 years of age have been reported to have hypertension. 

Hypertension is strongly associated with overall cardiovascular risk. Cardiovascular disease is the foremost cause of preventable deaths globally accounting for 30% of all deaths . However, approximately half of the disease burden attributable to office BP develops in individuals with hypertension; the remainder develops in those with BP values in the normal range . Masked hypertension, a condition with normal office and elevated out-of-office, is often missed in the office visit. . Read more>>>>>>>>>>>>