Although the association among
arterial rigidity, inflammation and atherosclerosis has been established, that
among systolic blood pressure variability (BPV, defined as blood pressure variation per unit time, inflammation and arterial rigidity is yet to be
elucidated.
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| Systolic Blood Pressure Variation |
The present study, which is the first to report simultaneous
measurements of BPV (assessed by coefficient of variation (CV) in ambulatory
blood pressure monitoring (ABPM)),
inflammation (as reflected by levels of high-sensitivity C-reactive protein (hs-CRP) and arterial
rigidity (assessed by brachial-ankle pulse wave velocity (ba-PWV) at baseline
and 1-year follow-up, is aimed at testing the hypothesis that greater blood
pressure variation (which is higher among hypertensive than normotensive
individuals translates into stronger shearing force on the arterial wall, which
could trigger inflammation (known to be involved in the pathogenesis and
progression of hypertension leading to
arterial rigidity. Read more>>>>>>>>>>
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