Stress Cardiomyopathy was Prone to Occur in Patients with Chronic Diseases

Stress Cardio Myopathy (SCM), also called Tako-tsubo cardiomyopathy, broken heart syndrome or apical ballooning syndrome,is commonly triggered by an acute strong physical or emotional stress. Its most typical symptoms include acute, severe and complete heart dysfunction with reversible favourable outcomes. As we all known, the cardiovascular disease is still the leading cause of death. 

 

Stress Cardiomyopathy

But the SCM has a very low death rate compared with acute coronary diseases or heart failure. So, in some situations, it was considered that this reversible SCM may be a cardioprotective strategy, to avoid heart failure diseases when emergency occurs. Despite the increasing recognization of SCM, the precise pathophysiology of SCM remains unknown. Read more>>>>>>>

Giant-Cell Arteritis: Immunopathogenic Mechanisms Involved in Vascular Inflammation and Remodeling

Giant-cell arteritis (GCA) is a granulomatous vasculitis affecting large and medium-sized vessels with a special tropism for the carotid and vertebral arteries. Involvement of the superficial temporal artery is very frequent and performance of temporal artery biopsies is a common diagnostic procedure which facilitates histopathological confirmation of GCA. 

Giant-Cell Arteritis

Temporal artery biopsies are also a source of valuable tissuenot only for diagnostic purposes but also for immunopathology studies which have provided important pathogenetic clues. In fact, the current pathogenesis model is essentially based on the demonstration of particular cell types and subsets in involved tissue or peripheral blood, the expression of activation and differentiation markers by these cells and the production of certain inflammatory molecules in lesions. Read more>>>>>>>>>

Aerococcus Urinae Infective Endocarditis-related Stroke

The patient was a 75 year old African-American man with a history of hypertension, hyperlipidemia, diabetes and chronic kidney disease who presented with a low grade fever and leukocytosis. His blood pressure was 167/76 mmHg, heart rate 102 BPM, and temperature 100.4⁰F. A II/VI diastolic murmur was present. 

Aerococcus Urinae

He was somnolent but easily arousal on presentation to the hospital. Neurological examination was otherwise notable for global aphasia, left gaze preference, right nasolabial fold flattening, and right lower extremity drift. Laboratory testing included a normal basic metabolic panel except for an elevated keratinize (2.3 mg/dL), BUN (24 mg/dL) and glucose (277 mg/dL). There was a neutrophil-predominant leukocytosis (WBC 16.5×109/L) and normocytic anemia (Hg 13.4 g/dL, MCV 91fL) with a normal platelet count. Read more>>>>>>>>>>>

Left Ventricular end Systolic and Diastolic Volumes and Ejection Fraction in Patients with Heart Failure and Preserved Ejection Fraction Meta and Graphical Analysis

It was previously reported using meta-analysis that EF in HFPEF is often “greater-than-normal”, that is greater than the EF in HC of the same age. The physiological basis for this finding is not clear, though a hypothesis was proposed. 

Heart Failure

Although remodeling processes in HFPEF, accounting for morphological changes in the LV, are well established, to the best of our knowledge investigations comparing how ESV, EDV and EF in HFPEF differ from their counterparts in HC were not published. Specifically, if EF in HFPEF (EFHFPEF) is greater than EF in HC (EFHC), the fraction ESV/EDV in HFPEF must be smaller than that in HC. The magnitude of ESV/EDV may decrease in one of several forms, yet the expected form is characterized by a decrease in EDV accompanied by a greater relative decrease in ESV. Read more>>>>>>>>

Eosinophilic Endomyocarditis: Rare Cases with Uncertain Prognosis

A 67-year-old patient presented in a rural hospital with an increasing fatigue and worsening of her general state of health. She had a known rheumatoid arthritis that was diagnosed in 1990. One year before she suffered from a first cerebral ischemia that recurred in the following months resulting in a sensomotoric hemiparesis. In addition she underwent Hemicolectomy with chemotherapy two months before the actual admission. 

Eosinophilic Endomyocarditis

The laboratory showed a leukocytosis, an eosinophilia and an increase in C-reactive protein. A transthoracic Echocardiogram showed two large thrombi in both ventricles and a moderately reduced function of both ventricles (visual EF=35-40%). Earlier coronary angiography did not show any pathology that could explain the reduced ventricular function. The rural hospital started a therapy with oral steroids (prednisone 60 mg) and transferred the patient to the university hospital for further diagnosis. Read more>>>>>>>>>>