Wednesday, 21 September 2016

Is it possible to prevent prevention of Preeclampsia?

Preeclampsia (PE) is one of the pregnancy related disorders; it is not clearly evident due to its complex signs and symptoms. It causes morbidity and mortality in women. Even the advanced research practised to reduce the morbidity and mortality has failed because of the multifactorial origin of the pathogenic process. Even developing a single biomarker for PE is difficult because of its heterogenecity. Initially anti-hypertensive drugs were used as it is the main symptom of PE but these drugs did not give any positive results. Some of the other drugs for PE includes calcium supplement,Acetylsalicylic acid etcbut are not up to the mark.

PreeclampsiaPreeclampsia (PE) involves dysfunction in pregnancy, with consequences of morbidity andmortality worldwide. The prevalence of PE is 5% to 8%. PE is characterized by systolic blood pressure (SBP) ≥ 140 mmHg or diastolic blood pressure (DBP) ≥ 90 mmHg as assessed on two occasions at least 4 hours apart. Additionally, PE is also characterized as the presence of proteinuria of >300 mg per 24 hours or when urinary dipstick proteinuria is ≥ 1, after 20 weeks of pregnancy, or in the absence of proteinuria, the first appearance of thrombocytopenia. PE is one of the major causes of maternal mortality, resulting in 50,000 to 60,000 deaths annually worldwide. This disease also increases the risk of complications in the mother and development of cardiovascular disease in later life in the newborn and the mother.Read more.............

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