Thursday, 29 September 2016

De Bukes Syndrome - Tetrology of Fallot with Absent Left Pulmonary Artery

De Buckes syndrome – TOF with unilateral absence of a pulmonary artery (UAPA) is a rare condition with an estimated prevalence of 1 in 200,000 young adults . Most commonly, UAPA occurs in conjunction with cardiovascular abnormalities such as tetralogy of Fallot (TOF) coarctation of the aorta, VSD, subvalvular aortic stenosis, transposition of the great arteries (plus VSD or pulmonary stenosis), Taussig-Bing malformation and coarctation, congenitally corrected transposition and pulmonary stenosis, scimitar syndrome. Patients with isolated UAPA can remain asymptomatic into late adulthood but usually report symptoms such as dyspnea or chest pain or suffer from hemoptysis or recurrent infections. Diagnosis can be difficult due to the rarity of the condition and its nonspecific presentation. We present a case of a 5month old child who presented with TOF with Right pulmonary artery stenosis and absent left pulmonary artery, with typical findings on chest radiograph, angiographic features and treatment discussed.
Tetrology of Fallot

Case Report: A five months old male child was referred to Sri Jayadeva Institute of Cardiovascular Science and research for cardiac evaluation. He was born to non-consanginous parents with normal pregnancy and normal delivery. He presented with history of incessant feeding and cyanosis while feeding and crying. On physical examination, the patient had cyanosis with SpO2 of 67%. There was no respiratory distress at rest. His weight was 3 kgs (just below the 5th percentile for his age). Heart rate was 104 beats/minute and blood pressure was 100/55 mmHg. Cardiovascular examination revealed normal peripheral pulses, the second heart sound was single and Grade 3/6 Ejection systolic murmer. The electrocardiogram showed sinus rhythm, right axis deviation and right ventricular (RV) hypertrophy. Chest X-ray showed mild cardiomegaly, with normal bronchovascular markings on right side and absent bronchovascular markings on left side. Read more.......... 

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