Atrial Fibrillation (AF) is the most common
sustained cardiac arrhythmia, and is associated with thromboembolic events.
Previous studies also have shown a close relationship between AF and heart
failure, and heart failure can be one of the most important risk factors for AF.
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Atrial Fibrillation |
Therefore, heart failure animal models have been established to investigate the
structural and electrical remodeling for AF substrates and suggested that the
structural and/or electrical remodeling caused by heart failure may play an
important role in AF genesis. Several recent studies have demonstrated that
Direct Oral Anticoagulants (DOACs) can directly modulate the mechanical and
electrophysiological properties of the Left Atrium (LA) and Pulmonary Veins
(PVs) and suggest that DOACs may have a beneficial effect of anti-AF actions
via preventing AF progression in addition to their anti-thrombotic action. Read More>>>>>>>>
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