Tuesday, 18 July 2017

The Effect of High-Dose Simvastatin Therapy on Patients with Acute Cerebral Infarction

Cerebrovascular disease (CVD) is the third most common cause of death worldwide. CVD accounts for the major cause of morbidity and mortality in industrialized countries and responsible for stroke and transient ischemic attack (TIA). 


There are about 500,000 new or recurrences stroke cases each year. Simvastatin (epistatin), an HMG-CoA reductase inhibitor, acts by decreasing cholesterol synthesis and by increasing low density lipoprotein (LDL) catabolism via increased LDL receptor activity. Simvastatin was beneficial in a lot of immunologic VCD. Evidences indicated that simvastatin could stable plaque and improve the long-term prognosis of patients with CVD. Read More>>>>>>>>

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