Systemic
Arterial Hypertension (hereafter referred to as ‘hypertension’) is defined as
blood pressure (BP) ≥140/90 mmHg. It is a major preventable cause of premature
mortality through its association with Cardiovascular Disease (CVD) and renal
disease. Hypertension-related CVD primarily includes stroke and Ischaemic Heart
Disease (IHD). Isolated Systolic Hypertension (ISH) is more common in the
elderly because the Diastolic Blood Pressure (DBP) plateaus in the 5th and 6th
decades and, subsequently, gradually declines, unlike the Systolic BloodPressure (SBP), which continues to increase with age.
Annually, approximately 8
million deaths worldwide are attributable to elevated SBP, accounting for about
14% of all deaths . This includes 54% and 47% of hypertension-attributable
deaths due to stroke and IHD, respectively. The risk of death from such
cardiovascular events (CE) increases in a ‘log-linear’ fashion for BP ≥115/75
mmHg, even in individuals with no known underlying vascular disease. For
instance, the probability of dying from CE such as IHD and stroke is doubled
for every 20 mmHg increase in SBP or 10 mmHg rise in DBP in middle-aged and
elderly persons. Read more>>>>>>>>>>>>>>>>>
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