Wednesday, 15 March 2017

The Relationship between Micro Albuminuria and Plasma Homocysteine Level in Chinese Patients with Hypertension

Chronic Kidney Disease (CKD) and its associated morbidity pose a worldwide health problem. Cardiovascular disease is the leading cause of premature death among the CKD population. Microalbuminuriais a marker of renal injury that can often be detected earlier than any tangible decline in glomerular filtration rate. 

Micro Albuminuria

As well as being a risk marker of renal dysfunction, micro albuminuria is now widely accepted as an independent risk factor for cardiovascular morbidity and mortality. The elevation of homocysteine (Hcy) level is now known as an independent risk factor for vascular diseases and hyperhomocysteinemia (Hcy) is more common in Chinese patients with hypertension due to their special genetic background. It can promote oxidant injury to the vascular endothelium, impairs endothelium-dependent vasomotor regulation, and may also alter the coagulant properties of the blood.  Read more>>>>>>>>>

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